Úlcera de Marjolin associada a ulceração e osteomielite crônicas

Squamous cell carcinoma in a laparostomy scar.

Cicatrização anormal pode levar à transformação maligna. Carcinoma de células escamosas de uma ferida crônica não cicatrizada é chamada de úlcera de Marjolin, e este processo é geralmente associado com queimaduras. Úlcera de Marjolin, em oposição ao câncer da pele espontâneo, é mais provável que ocorra nas extremidades, e tem padrão altamente agressivo, com 27,5% de pacientes desenvolvendo metá...

Ulcère de Marjolin

L’ulcère de Marjolin désigne la transformation maligne d’une cicatrice de brûlure ou de toute autre plaie ou ulcération chronique. Rare, son incidence est estimée à 2% des cas. Le type histologique prédominant reste le carcinome épidermoïde (75%). Les membres en particulier les plis de flexion sont le siège préférentiel en raison des contraintes mécaniques exposant à la ré-ulcération. La périod...

Doença de Castleman associada a derrame pleural

Castleman’s disease is a rare disorder of the lymphoid tissue. We report the case of a female patient with bilateral otosclerosis, no respiratory symptoms, and pleural effusion discovered as an incidental finding on a chest X-ray. Computed tomography of the chest revealed a mediastinal mass. The biopsy findings demonstrated that it was a plasmacytic variant of Castleman’s disease. The patient u...

Síndrome de restauração imune associada à histoplasmose

A 27-year-old HIV-positive male patient with disseminated cutaneous histoplasmosis was treated with both HAART and amphotericin B (total accumulated dose of 0.5g). Amphotericin B was later replaced with itraconazole (200mg/day). Two months after therapy had been started and the cutaneous lesions had healed, the patient interrupted both treatments voluntarily and his health deteriorated. HAART w...

Marjolin ulcer in a surgical scar.